Centre opened the season with three straight wins by a combined score of 241–0, beating Morris Harvey, 66–0; the Howard Bulldogs, 120–0; and Transylvania, 55–0.

Instead of punting, McMillin "defied every "don't" in the football book" and tossed a touchdown pass.

[15] One writer recalled he heard a story that Tech tackle Bill Fincher sought to knock Bo McMillin out of the game, taking with him brass-knuckles or "something equally diabolical.

"[16] Centre then defeated DePauw, 34–0, in Indianapolis;Kentucky, 49–0, at Lexington; VPI, 28–0, in Louisville; and the Georgetown Tigers, 103–0.

TCU entered the game with a record of 9–0, including wins at Arkansas (19–2) and at Baylor (21–9).