The 1950–51 Copa México was the 35th staging of the Copa México, the 8th staging in the professional era.
The competition started on May 6, 1951, and concluded on May 27, 1951, with the final, in which Atlante lifted the trophy for the second time ever with a 1–0 victory over Guadalajara.
This edition was played only by 12 teams, in a knock-out stage, in a single match.
Played between May 6 and May 8 Bye: Marte and Necaxa Played May 13 Bye: Atlante Played May 15 Played May 20 Played May 22 Played May 27