Frank Sedgman defeated Gardnar Mulloy 6–1, 6–2, 6–3 in the final to win the men's singles tennis title at the 1952 U.S. National Championships.

[2] The tournament used two lists of eight players for seeding the men's singles event; one for U.S. players and one for foreign players.

Frank Sedgman is the champion; others show the round in which they were eliminated.

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