The team had a record of 80–74 finishing in third place in the National League standings, twelve games behind the NL Champion Milwaukee Braves.

The Giants and the now-Los Angeles Dodgers, arch-rivals for 68 years in New York, faced each other in their respective first-ever game on the West Coast.

On Tuesday afternoon, April 15, 1958, at Seals Stadium, the Giants' temporary home park, San Francisco blanked Los Angeles, 8–0, behind Rubén Gómez' complete game, six-hit shutout.

Infielders Coaches Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.

= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts All-Star Game LEAGUE CHAMPIONS: Phoenix, Corpus Christi, Fresno[16]