It determined that year's club champion of association football in Africa.

Hafia FC from Guinea won the final, becoming CAF club champion for the first time and the first Guinean team to win the trophy.

1 After the match had finished 2-0 to Djoliba AC, leaving the aggregate level at 2–2, AS Forces Armées (Dakar) refused to take part in the penalty shootout to protest the officiating; they were ejected from the competition and banned from CAF competitions for three years.

1 TP Mazembe refused to play the 2nd leg contesting the eligibility of the referees assigned by CAF: TP Mazembe were ejected from the competition, and CAF awarded Hafia FC a 2–0 victory.

The top scorers from the 1972 African Cup of Champions Clubs are as follows: