The Cardinals went 83–79 during the season and finished third in the National League East, 18 games behind the Philadelphia Phillies.

Vern Rapp took over as the Cardinals' manager this year, after the twelve-year reign of their longtime manager Red Schoendienst.

On August 29, Cardinals left-fielder Lou Brock broke the modern-day stolen base record, by stealing bases 892 and 893 in a game against the Padres in San Diego.

Infielders Coaches Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.

= Batting average; HR = Home runs; RBI = Runs batted in Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; IP = Innings pitched; W = Wins; L = Losses; ERA = Earned run average; SO = Strikeouts Note: G = Games pitched; W = Wins; L = Losses; SV = Saves; ERA = Earned run average; SO = Strikeouts LEAGUE CHAMPIONS: Arkansas, Gastonia[19]