Nea Salamis Famagusta FC won their 2nd title.
[1] Fourteen teams participated in the 1979–80 Cypriot Second Division.
The team with the most points at the end of the season crowned champions.
The first team was promoted to 1980–81 Cypriot First Division.
The last two teams were relegated to the 1980–81 Cypriot Third Division.