The 1981 Little League World Series took place between August 25 and August 29 in South Williamsport, Pennsylvania.

The Taiping Little League of Taichung, Taiwan, defeated the Belmont Heights Little League of Tampa, Florida, in the championship game of the 35th Little League World Series (LLWS).

This was the fifth consecutive title for Taiwan, which remains the longest LLWS winning streak by any single country or U.S. state.