They played their home games at Oklahoma Memorial Stadium and competed as members of the Big Eight Conference.

The Sooners defeated the Houston Cougars 40–14 to win the 1981 Sun Bowl in El Paso, Texas.

[13] Roster at Lewis Field • Stillwater, Oklahoma Fred Sims scored three short-yardage touchdowns to lead Oklahoma to a 27–3 win over their instate rivals in a steady drizzle.

[14] The following players were drafted into the National Football League following the season.

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