The 1990 Mexican Grand Prix was a Formula One motor race held at Autodromo Hermanos Rodriguez on 24 June 1990.

Ayrton Senna stopped with a puncture late in the race, allowing both Prost and Berger to close to eight points behind him in the Driver's Championship.

For the third Grand Prix in succession, the AGS cars missed out in fifth and sixth positions, with Yannick Dalmas faster than Gabriele Tarquini this time.

Claudio Langes was a distant eighth again after only completing the minimum three laps required by the regulations, as the team concentrated on Moreno.

At the front of the grid, Gerhard Berger took pole from Riccardo Patrese, Ayrton Senna, Nigel Mansell, Thierry Boutsen, Jean Alesi, Pierluigi Martini, Nelson Piquet, Satoru Nakajima, and Stefano Modena, with championship contender Alain Prost, not happy with the qualifying set up of his Ferrari so deciding instead to qualify with his race set up, 13th.

Senna and Berger both passed Patrese on lap 2, and the McLaren drivers opened a significant lead over the rest of the field.