The 1991 First Union 400 was the seventh stock car race of the 1991 NASCAR Winston Cup Series and the 41st iteration of the event.

It measures 0.625 mi (1.006 km) and features a unique uphill backstretch and downhill frontstretch.

The speedway briefly reopened in 2010 and hosted several stock car series races before closing again in the spring of 2011.

*After sustaining burns in a crash at the 1991 Valleydale Meats 500, Sterling Marlin would be replaced by relief driver Charlie Glotzbach for qualifying.

Brett Bodine, driving for King Racing, would win the pole, setting a time of 19.357 and an average speed of 116.237 miles per hour (187.065 km/h).