The 1998–99 Louisiana Tech Lady Techsters basketball team represented Louisiana Tech University during the 1998–99 NCAA Division I women's basketball season.

The team was led by head coach Leon Barmore, who guided the team to a 30–3 record and an appearance in the 1999 NCAA tournament.

The team reached one last Final Four appearance during Barmore's stellar career.

[1] This was the program's tenth appearance in the Final Four.

The team played their home games at the Thomas Assembly Center in Ruston, Louisiana as a member of the Sun Belt Conference.