The 1999–2000 George Mason Patriots Men's basketball team represented George Mason University during the 1999–2000 NCAA Division I men's basketball season.
This was the 34th season for the program, the third under head coach Jim Larrañaga.
The Patriots played their home games at the Patriot Center in Fairfax, Virginia.
Colonial Athletic Association Player of the Year Colonial Athletic Association All-Conference Team Colonial Athletic Association All-Defensive Team Colonial Athletic Association Dean Ehlers Award