The 1999 NCAA Division I men's ice hockey tournament involved 12 schools in playing in single-elimination play to determine the national champion of NCAA Division I.

A total of 11 games were played, the final 3 at the Arrowhead Pond (now the Honda Center) in Anaheim, CA.

The University of Maine defeated New Hampshire by a score of 3–2 in overtime, to claim their second national championship.

The Central Collegiate Hockey Association (CCHA) had four teams receive a berth in the tournament, Hockey East and Western Collegiate Hockey Association (WCHA) each had three teams receive a berth in the tournament, while the ECAC had two berths.

Number in parentheses denotes overall seed in the tournament.