They failed to improve on their 9–7 record from 1999 and finished the season 7–9, marked by a series of on and off-field struggles and incidents.
In the offseason, 9-time Pro Bowl linebacker, team captain, and fan favorite Derrick Thomas died.
He was the first of three active NFL players to die in the 2000 offseason, along with Raiders safety Eric Turner (cancer) and Panthers running back Fred Lane (homicide).
He died of a pulmonary embolism that occurred due to becoming paralyzed following a January car accident.
The Chiefs gave the San Diego Chargers their only victory of the season, losing to them in Week 13.
Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve at Adelphia Coliseum, Nashville, Tennessee First quarter Second quarter Third quarter Fourth quarter Top passers Top rushers Top receivers