The 2001 Abierto Mexicano Pegaso was a tennis tournament played on outdoor clay courts at the Fairmont Acapulco Princess in Acapulco in Mexico that was part of the International Series Gold of the 2001 ATP Tour and of Tier III of the 2001 WTA Tour.

The tournament was held from February 26 through March 4, 2001.

Gustavo Kuerten defeated Galo Blanco 6–4, 6–2 Amanda Coetzer defeated Elena Dementieva 2–6, 6–1, 6–2 Donald Johnson / Gustavo Kuerten defeated David Adams / Martín García 6–3, 7–6(7–5) María José Martínez / Anabel Medina Garrigues defeated Virginia Ruano Pascual / Paola Suárez 6–4, 6–7(5–7), 7–5