The 2001 Italian motorcycle Grand Prix was the fifth round of the 2001 Grand Prix motorcycle racing season.

It took place on the weekend of 1–3 June 2001 at the Mugello Circuit.

The race was held in two parts as rain caused its interruption; aggregate times from the two heats determined the final result.

[3] Below are the standings for the top five riders and constructors after round five has concluded.

[9]