[1] Notes Before the start of the first inning, Alex Rodriguez voluntarily elected to switch to third base to allow Cal Ripken Jr. to play at the shortstop position one final time at the All-Star Game, which the crowd gave a standing ovation.

Seattle's own Ichiro Suzuki gave his hometown fans something to cheer for early, when in the first, he singled off starter (and former Mariner) Randy Johnson, and then stole second.

The AL scored one more run in the fifth when Iván Rodríguez singled home Jason Giambi to make it 2–0.

Ryan Klesko hit a sacrifice fly to cut the lead to one in the sixth, scoring Jeff Kent from third.

Mariner closer Kazuhiro Sasaki retired the side in order in the ninth to secure the win for the AL. Cal Ripken was awarded the game's MVP, becoming the fourth player ever—and first from the American League—to win two All-Star Game MVP awards.