The 2004–05 Southeastern Louisiana Lions basketball team represented Southeastern Louisiana University during the 2004–05 NCAA Division I men's basketball season.

The Lions, led by sixth-year head coach Billy Kennedy, played their home games at the University Center in Hammond, Louisiana as members of the Southland Conference.

They finished the season 24–9, 13–3 in Southland play to finish in a tie for the Southland regular season championship with Northwestern State.

2 seed in the Southland tournament, they defeated Texas State, Sam Houston State, and Northwestern State to earn the conference's automatic bid to the NCAA tournament – the first,[1] and only, appearance in program history.

2 seed Oklahoma State in the opening round.