The game was held on July 13, 2004, at Minute Maid Park in Houston, Texas, the home of the Houston Astros of the National League.

The game resulted in the American League defeating the National League 9–4, thus awarding the AL home-field advantage in the 2004 World Series.

Players in italics have since been inducted into the National Baseball Hall of Fame.

Notes The Canadian national anthem was sung by The Tragically Hip lead vocalist Gord Downie.

The American national anthem was sung by American Idol Season 3 winner Fantasia Barrino.