The Red Sox scored their only runs of the game in the fourth when Trot Nixon and Jason Varitek hit back-to-back singles aided by an error to put them on third and second, respectively.

In the bottom of the fourth, Juan Uribe's two-run home run extended Chicago's lead to 8–2 and forced Clement out of the game.

U.S. Cellular Field in Chicago, Illinois The Red Sox struck first in Game 2 on Manny Ramirez's two-run single off of Mark Buehrle with runners on second and third.

In the sixth, Paul Konerko, with Jermaine Dye on base, hit a home run to put the White Sox in the lead for good.

Ramirez's second home run of the game in the bottom of the inning cut the lead to 4–3, then Damaso Marte relieved Garcia and allowed a single and two walks to load the bases with no outs.

The White Sox got an insurance run in the ninth off of Mike Timlin when A. J. Pierzynski hit a leadoff double, moved to third on a groundout and scored on Juan Uribe's fielder's choice.

Three two-out singles loaded the bases in the top of the first, then rookie Robinson Canó lifted a line drive over the reaching hand of left fielder Garret Anderson.

Though Colón and Scot Shields held the Yankees scoreless for the rest of the game, starter Mike Mussina pitched 5+2⁄3 innings.

After stealing second, Guerrero scored on Darin Erstad's single, but Rivera retired the next two batters to give the Yankees a 1–0 series lead.

They made it 2–0 in the fifth after Alex Rodríguez walked, moved to third on Jason Giambi's double and scored on Gary Sheffield's ground out.

In the ninth, Jorge Posada's home run off of Francisco Rodriguez cut the lead back to two, but K. Rod retired the next three batters to end the game and tie the series heading to New York.

After a walk, Brendan Donnelly relieved Byrd and Jason Giambi's single scored Jeter and cut the Angels' lead to one.

In the eighth, Leiter allowed a leadoff triple, then after a one-out intentional walk, back-to-back RBI singles by José Molina and Anderson off of Scott Proctor made it 11–6 Angels.

The Yankees cut the lead to one in the bottom of the inning when Alex Rodriguez walked, moved to second on a groundout and scored on Gary Sheffield's single off Angels starting pitcher John Lackey.

Al Leiter earned the win in relief and Mariano Rivera pitched a perfect eighth and ninth as the Yankees won 3–2 to force a Game 5 back in Anaheim.

Williams scored on Bubba Crosby's single and Posada on Derek Jeter's sacrifice fly as the Yankees took an early 2–0 lead.

Bubba Crosby and Gary Sheffield collided on the outfield wall trying to catch it, allowing Molina and Finley to score to give the Angels a 3–2 lead.

Next inning, Mussina allowed back-to-back leadoff singles to put runners on first and third, then Anderson's sacrifice fly scored a run.

Jason Giambi and Gary Sheffield both hit singles afterward, but Hideki Matsui grounded out to first to end the game.