The 2005 CAF Confederation Cup was the second edition of the CAF Confederation Cup.

It started with the preliminary round (home-and away ties) that was played in January and February 2005.

FAR Rabat of Morocco beat Dolphins F.C.

The top scorers from the 2005 CAF Confederation Cup are as follows.

Eric Gawu/Khalid El Hirech/Kelechi Osunwa