The 2005 Pocono 500 was the 14th stock car race of the 2005 NASCAR Nextel Cup Series and the 24th iteration of the event.

The race was held on Sunday, June 12, 2005 at Pocono Raceway in Long Pond, Pennsylvania, a 2.5 miles (4.0 km) triangular track that holds NASCAR races to this day.

[1] Rookie Carl Edwards would win the race under caution, his second of the season and his career after originally starting 29th, proceeding to lead 46 laps.

For pre-race ceremonies, the invocation was given out by Father Dan Bisco.

The national anthem would be performed by the United States Army Chorus.