Thirty-three teams from eighteen football associations took part, starting with the first qualifying games on July 26, 2005.

The tournament ended with a two-legged final between Mexican teams América and Toluca.

The first leg was played at Estadio Nemesio Díez in Toluca, Mexico on April 12, 2006 and ended in a 0–0 draw.

The second leg was played at Estadio Azteca in Mexico City on April 19, 2006 and ended with América scoring in extra time for a 2–1 win, therefore the Mexican side achieved their fifth CONCACAF trophy.

[1][2] With the victory, América qualified for the 2006 FIFA Club World Cup held in Japan.