The 2006 Espirito Santo Trophy took place 18–21 October at De Zalze Golf Club and Stellenbosch Golf Club in Stellenbosch in the Western Cape province of South Africa.

It was the 22nd women's golf World Amateur Team Championship for the Espirito Santo Trophy.

The team of the hosting nation South Africa won the Trophy for their first title.

Silver medalist and defending champions, team Sweden, had the same total score, but South Africa was declared the winner.

The individual title went to Caroline Westrup, Sweden, whose score of 8-under-par, 280, was two strokes ahead of Rikako Morita, Japan.