Early pre-season was dominated by the protracted talks involving the renewal of Cristian Chivu's contract[2] and the many rumours that linked him to many other teams.

[3] For this reason in early June Roma extended Philippe Mexès' contract until 2011[4] and signed Brazilian 2007 Copa América winning defender Juan from Bayer Leverkusen.

The player also turned down offers from Barcelona and Real Madrid,[5] stating that if he was not transferred to Inter he would keep playing for Roma until his contract ran out the summer of 2008.

[8] Eventually, on 27 July, when it seemed that Chivu would have been a giallorosso until the end of his contract period, Inter made a final offer of 14M€ plus the co-ownership of Marco Andreolli.

The signings of Matteo Brighi, Ahmed Barusso, and Vitorino Antunes further enlarged the squad, while young players such as Aleandro Rosi, Ricardo Faty, Stefano Okaka, Valerio Virga, Alessio Cerci, Andrea Giacomini and Daniele Galloppa were loaned to lower league clubs to gain experience.

After the pause for Italy's Euro 2008 qualifying matches against France and Ukraine, in which Daniele De Rossi, Simone Perrotta, Christian Panucci and Alberto Aquilani played, Roma entered a difficult period of fixtures over a short span of time: from 16 September until 3 October, the giallorossi played against Reggina (winning 2–0), Dynamo Kyiv (winning 2–0), Juventus (drawing 2–2), Fiorentina (drawing 2–2), Internazionale (losing 4–1) and Manchester United (losing 1–0).

[14] - After losing their position as Serie A league leaders, Roma had to face Manchester United for the first time since their débâcle the previous season at the hands of the English champions in the quarter-finals where they had lost 7–1 .

[19] On 31 October 2007 the giallorossi played the Derby della Capitale against Lazio without three important first team players (Totti, Alberto Aquilani and Rodrigo Taddei), all out with injury.