The team was coached by Randy Edsall and played its home games at Rentschler Field in East Hartford, Connecticut.

[1][2] In a game that was a tale of two halves, the Huskies started the season with a 45–14 win against Duke, extending the Blue Devils' winless streak to twenty-one straight.

On the final play of the game, Temple ran a wide receiver reverse pass, which was batted down in the end zone by UConn defensive back Robert Vaughn.

The replay angle which could have provided the conclusive evidence, both foot inbounds and possession, was obstructed by a security guard standing in the line of sight of the television camera.

Returning home to East Hartford, the Huskies held off the Zips to win their fifth straight game for the first time since 1995.

The Huskies again returned to the friendly confines of Rentschler Field for a heavily anticipated match-up with conference foe Louisville.

After a defensive stop, the Huskies drove down the field, and Andre Dixon scored the game-winning touchdown with 1:32 left to play.

Linebacker Danny Lansanah cemented the victory picking off Cardinals quarterback Brian Brohm with 15 seconds to play.

Back in East Hartford for the second of three straight home games, the Huskies looked to make a statement against 10th ranked South Florida.

Midway through the second quarter, Quarterback Tyler Lorenzen hooked up with TE Steve Brouse for a three-yard touchdown pass.

South Florida finally lit up the scoreboard with just over six minutes to play in the third quarter on a blocked punt, which was covered up in the endzone by the Huskies for a safety.

After the punt, Uconn progressed to drive down the field as junior college transfer Tyler Lorenzen hit Steve Brouse on a short two yard out route in the endzone.

Uconn had good field possession late in the first quarter and Lorenzen hooked up with wide out Terrence Jeffers for 34 yards.

Uconn drove again and with Andre Dixon out of the game, the ball was handed to sophomore Donald Brown who found a large hole on the right side and took it for a 33-yard touchdown.

Ray Rice was held to less than 30 yards in the second half and Tyvon Branch was subsequently named Big East special teams player of the week.

West Virginia's blowout victory over the Huskies resulted in a sarcastic running joke in the UConn student paper, the Daily Campus.

Variations on the joke, "West Virginia just scored again," began running in the paper's InstantDaily feature the Monday following the game and continued well into the Spring 2008 semester.