The 2008 Best Buy 400 benefiting Student Clubs for Autism Speaks was the thirteenth race of the 2008 NASCAR Sprint Cup schedule which was run on Sunday, June 1 at Dover International Speedway in Delaware's state capital, and serves as a fundraiser for Autism Speaks, with $5 from each ticket sold benefitting the charity.

Greg Biffle earned his 5th Cup Career pole by qualifying first for the Best Buy 400, with a time of 23.193 and a speed of 155.219.

Starting alongside him was Kurt Busch, the 2004 NASCAR Nextel Cup Series Champion, with a time of 23.381.

Clint Bowyer, Kasey Kahne, Denny Hamlin, Paul Menard, Elliott Sadler, Tony Stewart, Bill Elliott, Kevin Harvick, Bobby Labonte, Scott Riggs, and Dale Earnhardt Jr. were all caught up in the wreck.

When the smoke cleared, Kyle Busch won his fourth race of 2008.