The 2009–10 Siena Saints men's basketball team represented Siena College in the 2009–10 college basketball season.
This was head coach Fran McCaffery's fifth season at Siena.
The Saints competed in the Metro Atlantic Athletic Conference and played their home games at Times Union Center.
They also won the 2010 MAAC men's basketball tournament for the third consecutive year to earn the conference's automatic bid to the 2010 NCAA Division I men's basketball tournament.
In the MAAC preseason poll, released October 27 in Edison, New Jersey, Siena was predicted to finish first in the MAAC.