[17] Sam Bradford, Brody Eldridge, Gerald McCoy and Ryan Reynolds served as team captains for the 2009 squad.

[19][20][21][22]Roster Last update: November 16, 2009 The Sooners opened the season on the road in the newly constructed Cowboys Stadium in Arlington, Texas against the 20th ranked program in the country.

[24] This was only the second time these teams had faced each other, the first coming in the 1994 Copper Bowl when the #22 ranked Cougars threw for 485 yards and defeated the Sooners 31–6.

Senior Mike Balogun experienced legal issues when his eligibility was called into question and subsequently decertified to participate in the 2009 season by the NCAA.

On BYU's last possession of the half, quarterback Max Hall completed a 49-yard pass to Bryan Kariya which left the Cougars 5 yards short of the end zone.

Despite the short yardage, Oklahoma and redshirt freshman quarterback Landry Jones were unable to capitalize and settled for a field goal to extend their lead to 13–7.

The Oklahoma defense held the BYU offense back for a while, forcing the Cougars to execute seven plays within the seven-yard line before finally succumbing.

With backup quarterback Landry Jones making his first start, Oklahoma won 64–0 for their 25th consecutive win at home, tying the school record.

Oklahoma would end the first quarter up 21–0 after the OU defense sacked the Idaho State quarterback, forcing a fumble, which was returned for a touchdown.

Oklahoma took possession and managed to progress to Tulsa's five-yard line, but, due to penalties, lost yardage and had to settle for a field goal.

Starting at their own two-yard line, Oklahoma was unable to progress and was forced to punt the ball back to Tulsa who subsequently missed a 50-yard field goal.

[50] Much of the pre-game hype had surrounded whether Oklahoma starting quarterback Sam Bradford would return after suffering an injury in the season opener.

Early in the second quarter, Oklahoma made its way to the Miami 4-yard line but was unable to score a touchdown and instead settled for a field goal to give them a 10–0 lead.

Following a fumble that Miami was able to regain, Harris completed an 18-yard pass to Jimmy Graham for a touchdown to bring the score to 10–7, with Oklahoma still on top.

[57] For the second week in a row, much of the pre-game talk had been on whether Oklahoma quarterback Sam Bradford would return following an injury sustained in the first game of the season.

[63] Texas came into the game undefeated, ranked number 3, and with two Heisman contenders: quarterback Colt McCoy and receiver Jordan Shipley.

During the first possession of the game, Oklahoma drove from their own 14-yard line to the Texas nine primarily on a 64-yard pass from QB Sam Bradford to RB DeMarco Murray but was unable to capitalize with a touchdown on three attempts and had to settle for a field goal giving them the early lead, 3–0.

On the ensuing Texas possession, the Oklahoma defense sacked McCoy, forcing a fumble, which was picked up by linebacker Ryan Reynolds.

After a couple passes from Jones to Brandon Caleb and Cameron Kenney, Oklahoma was again inside the Texas 20-yard line, where they again settled for a field goal.

After an Oklahoma three-and-out, Texas scored the first touchdown of the game on a drive that consisted of 12 plays, capped off with a 14-yard pass from McCoy to Marquise Goodwin.

Midway through the fourth quarter, Oklahoma running back Jermie Calhoun fumbled the ball and Kansas recovered at their own 45-yard line.

[75] The day after the game, Sam Bradford announced he would have season-ending shoulder surgery and would enter April's NFL draft.

Kansas State, coached by Bob Stoops' mentor, Bill Snyder,[77] traveled to Norman as the leader in the Big 12 North.

[79][80] The second half saw the Wildcats surge — scoring a touchdown and a two-point conversion on their opening possession to cut the Sooner lead to 28–17.

On the ensuing kick off, Kansas State's Brandon Banks caught the ball at the 2-yard line and returned it for a touchdown to again cut the Sooner lead back to five.

[19] Following the loss to Nebraska, Oklahoma returned home to play the Texas A&M Aggies, led by second-year head coach Mike Sherman.

Following the kickoff, Landry Jones threw a pass that was tipped and intercepted by A&M's Michael Hodges, who returned it 28 yards to the Oklahoma 6-yard line.

[86][87] For the final road game of the regular season, Oklahoma traveled to Lubbock, Texas where they had lost their previous two trips.

OSU wide receiver Dez Bryant was ruled ineligible by the NCAA in the weeks prior to the Bedlam game.

During an Oklahoma possession late in the first quarter, an incomplete pass to Dejuan Miller was ruled a fumble but was overturned following an instant replay analysis.