In Canada, roughly 10% of the populace (or 3.5 million) has been infected with the virus,[2][3] with 428 confirmed deaths (as of 20 February 2017);[1] non-fatal individual cases are for the most part no longer being recorded.

[2][5] The widespread effect of H1N1 in Canada raised concerns during the months leading to the XXI Olympic Winter Games, which took place in Vancouver in February 2010.

[7] On 2 May 2009, Canadian Food Inspection Agency executive vice-president Brian Evans announced that an infected Alberta farm worker recently returned from Mexico had apparently passed the virus to a swine herd in his care.

Lower Mainland who had recently come back from Mexico, according to Danuta Skowronski, head of flu and respiratory illnesses at the BC Centre for Disease Control, run by the provincial government.

The cases were discovered by normal flu testing conducted by the disease control centre after the men had visited a doctor about flu-like symptoms.

[18] The first fatality in British Columbia caused by the H1N1 virus occurred on 14 July, and was a young child who died within 24 hours of being rushed to the hospital.

[19] There were concerns of H1N1 during the months leading up to the 2010 Winter Olympics that occurred in Vancouver in February 2010, as a result volunteers were required to be vaccinated.

The second case, a Winnipeg woman in her 50s was admitted to hospital, although the province noted she also has an unidentified underlying medical condition.

The case involves a sample collected from a young man who was treated Thursday 11 June at the hospital in Grand Falls-Windsor.

[36][37] The Toronto region acted as a secondary epicentre during the 2003 SARS epidemic, and took extra precautions against the H1N1 virus in the early stages of the pandemic.

A two-month-old baby was admitted to the London Health Sciences Centre on 2 November 2009; the boy died in the early morning two days later.

[57] Later that day, the Federal Government confirmed the existence of a total of six cases in Canada; four in Nova Scotia and two in British Columbia.

She also said she had been in contact with her provincial and territorial counterparts and had ordered the Public Health Agency of Canada to alert border authorities, quarantine officers and other officials.

[58] However, Canada's Chief Public Health Officer, David Butler-Jones, stated that the six affected Canadians suffered from only mild symptoms and have already started to recover.

[60] In a step towards understanding the outbreak, and developing a vaccine, Canadian scientists completed the first full genetic sequencing of the H1N1 swine flu virus on 6 May.

[61] The high percentage of mild to severe cases amongst First Nations Peoples in Manitoba and Northern Ontario, when compared to the general population, have raised questions about the vulnerability of these communities to H1N1 across Canada.

[62][63] Concerns have also risen about whether the Canadian government's pandemic preparation plan is able to properly address the specific needs of these communities.