The 2010 Calgary Stampeders season was the 53rd season for the team in the Canadian Football League and their 72nd overall.

The Stampeders finished in first place in the West Division with a 13–5 record.

They attempted to win their 7th Grey Cup championship, but they lost in the West Final.

Running backs Wide receivers Slotbacks Defensive linemen Defensive backs Special teams Practice Roster Italics indicate Import player Roster updated 2010-10-30 Depth Chart • Transactions 46 Active, 8 Inactive, 8 PR → More rosters [1] [2] [3] *-Team won in Overtime.