The 2010 US Open was a tennis tournament played on outdoor hard courts, held from August 30 to September 13, 2010, in the USTA Billie Jean King National Tennis Center at Flushing Meadows, Queens, New York City, United States.

1 Serena Williams officially announced her withdrawal from the US Open on August 20 due to foot surgery.

[5] Her withdrawal also meant that she and older sister Venus could not pair up to defend the doubles title they won in 2009,[6] and allowed WTA No.

2 Caroline Wozniacki to be installed as the top seed for the tournament,[7] where she was defeated in the semi-finals by Vera Zvonareva.

Venus Williams, Maria Sharapova, Ana Ivanovic, Kim Clijsters and John Isner had all been in doubt after suffering minor injuries during lead-up tournaments but all were cleared to play.

[9] In a second round match played in 104 °F (40 °C) heat, Belarusian 10th seed Victoria Azarenka collapsed whilst trailing Gisela Dulko 1–5 in the first set.

Azarenka was subsequently taken to hospital in a wheelchair where she was diagnosed with mild concussion and later released a statement saying that a mishap in the gym, and not the heat, caused her to collapse during the match.

[12][13] Of the sixteen Spaniards that started in the 128-man draw, six of them reached the fourth round: Rafael Nadal, Fernando Verdasco, Tommy Robredo, David Ferrer, Feliciano López and Albert Montañés.

There were two all-Spanish fourth round matches, guaranteeing two Spaniards in the quarter-finals: Nadal vs. López and Ferrer vs. Verdasco (the latter winning in a final set tiebreak).

It was a doubles only event for the first time, but employed the fan-friendly World TeamTennis format for the second consecutive year.

Also scheduled to compete were U.S. Fed Cup Captain and two-time Grand Slam singles finalist Mary Joe Fernández, 1989 French Open champion Michael Chang, 1987 Wimbledon champion Pat Cash, 1997 French Open champion Iva Majoli, 1996 Wimbledon runner-up MaliVai Washington and 1999 US Open finalist Todd Martin.