It was the 23rd edition of the event known that year as the Atlanta Tennis Championships and was part of the ATP World Tour 250 series of the 2010 ATP World Tour.

The Atlanta Tennis Championships was the first ATP stop of the 2010 US Open Series.

Mardy Fish won the singles title.

Mardy Fish defeated John Isner, 4–6, 6–4, 7–6(7–4) Scott Lipsky / Rajeev Ram defeated Rohan Bopanna / Kristof Vliegen, 6–3, 6–7(4–7), [12–10] *Seedings based on the July 12, 2010 rankings and is subject to change.

The following players received wildcards into the singles main draw The following players received entry from the qualifying draw: