It was their first season in the Belgian Pro League after being promoted from the Belgian Second Division and the first time in 61 years a team from the city of Leuven played in the highest division.

The team kits for the 2011–12 season were produced by Vermarc and the main shirt sponsor was Option.

OHL's first season in the Belgian Pro League began on 29 July 2011.

Source: [citation needed] Points at home: 20 Points away from home: 9 Points against 2010/11 Playoff 1 teams (6): 12 Points against 2010/11 Playoff 2 teams (8): 13 Points against newly promoted teams (1): 4 Biggest home win: 3–1 vs. Mons; 3–1 vs. Club Brugge; 3–1 vs. Sint-Truiden Biggest home defeat: 1–3 vs. Standard Liège; 0–2 vs. Kortrijk Biggest away win: 1–3 vs. Westerlo Biggest away defeat: 6–1 vs. Gent; 5–0 vs. Genk Biggest home attendance: 8,519 vs. Club Brugge and vs. Standard Liège Smallest home attendance: 5,672 vs. Mons Biggest away attendance: 24,806 vs. Club Brugge Smallest away attendance: 4,000 vs. Mons

After finishing 14th during the regular season, OHL was placed in Group A of the Europa League Playoff together with Cercle Brugge, Lierse and Mechelen.