Following a loss on the final day of the regular season at home against Club Brugge, OH Leuven dropped into 16th place and was relegated as Westerlo beat Waasland-Beveren.

[12] In July, manager Jacky Mathijssen brought in 21-year old Greek defender Konstantinos Rougalas, who he had worked with two years earlier when they were together at Fostiras[13] and announced the loan deals of no less than four midfielders: Samuel Asamoah,[14] Kenneth Houdret,[15] Leandro Trossard[16] and Slobodan Urošević.

Towards the end of the summer 2015 transfer window, OH Leuven loaned Ukrainian defender Oleksandr Volovyk from Shakhtar Donetsk[18] and signed wingback Pieterjan Monteyne[19] and striker Kim Ojo.

[20] This in turn led to the departure of Olivier Lusamba who was given a free transfer,[21] while both Yohan Brouckaert[22] and Kenneth Van Goethem[23] were loaned out to Belgian Second Division teams as they were unlikely to be getting much time on the field.

They first confirmed extended partnerships with Rayden Transport,[33] Tegelconcept,[34] GMS-Group[35] and Dataflow[36] before announcing Just Eat as the new lead shirt sponsor replacing Option, the company led by former OHL chairman Jan Callewaert.

[44] Four days later against a very defensive Kortenberg, also playing in the sixth division, the match went much more difficult, with OHL only managing to score two goals prompting coach Jacky Mathijssen to state that "it was a bit dull" and that "he expected more of his players".

[48] On 15 July 2015, a 1-1 draw was obtained against Belgian Fourth Division team Tessenderlo in a match which featured mostly the players that had not received much playing time thus far, including a first starting lineup position for new striker Romero Regales.

[52] The seventh round saw OH Leuven play away at Mouscron-Péruwelz, in a game which took place just three days before the important relegation clash against Westerlo, causing Emilio Ferrera to leave regulars John Bostock, Yohan Croizet, Flavien Le Postollec, Jordan Remacle and Leandro Trossard out of the starting lineup.

In a dull second half, the OH Leuven players seemed to be thinking more of the upcoming clash with Westerlo not creating chances, while Mouscron-Péruwelz was happy to defend their one-goal lead instead of pushing for more.

The traditional friendlies occurred early September (against Genk) to bridge the gap caused by the international matches and in the beginning of January following the short winter break.