The 2011–12 Topklasse season was the second edition of the Dutch league since its inception in 2010.
A total 32 teams competed in the league: 24 from the 2010–11 Topklasse, and the remaining eight from the 2010–11 Hoofdklasse.
Promotion to the higher tier for a Topklasse requires it to switch into full professionalism and play on Friday nights instead of either Saturday or Sunday afternoons.
As neither them nor runners-up Spakenburg applied for that, no Topklasse team was promoted to 2012–13 Eerste Divisie.
Harkemase Boys and SVZW both finished the season with 25 points.