2011 Copa Sudamericana preliminary stages

[2] Sixteen teams (all from rest of South America) competed in the First Stage, where they were drawn into eight ties.

The following criteria were used for breaking ties on points: The fifteen winners of the Second Stage advanced to the round of 16 to join the defending champion Independiente.

Note: The second leg was suspended at the start of the second half by the referee after a projectile hit a linesman.

Tied on points 3–3, Vasco da Gama won on away goals.

Note: The second leg was abandoned after 81 minutes by the referee due to objects thrown onto the field.

Tied on points 3–3, São Paulo won on goal difference.