A promising start by OH Leuven and a 5-match winning streak in October resulted in a third place after 13 matchdays, but thereafter the team dropped in the standings to finally end 10th.

Both Wingback Lionel Gendarme and central defender Pieter Nys decide to sign with a second division team.

Through a web poll, the OHL fans chose François Sterchele as the player having the most merit during the ten inaugural years.

Other players completing the top 5 were (in order): Bjorn Ruytinx, Jordan Remacle, Joeri Vastmans and Hans Goethuys.

[6] After signing Günther Vanaudenaerde from Westerlo earlier, OHL confirms also the signing of Westerlo youngster Wout Bastiaens on June 5 [7] and announces a few days later that another promising youngster joins the squad as Ben Yagan (17) is promoted from the reserve team to the first team for the coming season.

[14] In need of a new goalkeeper since the departure of Thomas Kaminski following the end of the previous season, OHL finally choose to sign Logan Bailly.

With Bailly, OHL sign a 26 year old Belgian international goalkeeper, who has already gained 8 caps for the Red Devils.

After some less successful loans, Bailly now moves to OHL, hoping to relaunch his career under Ronny Van Geneugden, who he knows from his period at Genk.

Ruytinx, who had just signed a one-year contract extension in March 2012 to perform one more season for Oud-Heverlee Leuven, is now expected to be out for about 6 months.

Following weeks of rumours considering the future of Remacle, who requested a transfer and even handed in a doctors note to allow him to stay absent from training, the deal is now complete.

[23] OHL presents the team kits for the new season, the main difference being that the logo of head sponsor Option is now blending in with the shirt.

[25] Playing for the first time in their new kits, the team bounce back from trailing 0–2 with 15 minutes to go, to draw 2–2 with Genk in their first home match of the season.

Defender Nicky Hayen and midfielders Kevin Roelandts and Jorn Vermeulen join the Antwerp team for one season,[28] while Christian Pouga is presented as the latest new signing.

Eventually the match against the new team of Jordan Remacle ends in a 1–1 draw, a small revenge for OHL after the 6–1 loss during the previous season.

[32] Against an Anderlecht squad in which no less than 8 first team players have been replaced to keep them fresh for their upcoming Champions League fixture, OHL draws 1–1 at Den Dreef.

For the fifth game in a row, Ibou gets on the scoresheet, thereby taking the lead in the goal scorer standings,[33] however he also suffers an injury, causing him to be sidelined for about a week.

On the last day of the transfer window, OHL confirmed the signing of the 23-year-old Zimbabwean midfielder Ovidy Karuru from French side US Boulogne.

With just under ten minutes to play, Zulte Waregem scores the only goal of the match to give OHL a first home loss of the season.

Against Oostende, a red card for Ludovic Buysens and a handling error by Logan Bailly leading to the opening goal allow the second division team to eventually win easily, by a score of 2–1.

[44] The fourth win is achieved away to Beerschot, where OHL struggled for an hour until Kenneth Van Goethem put the ball past Stijn Stijnen.

In the latter match, an error by Jonas De Roeck allows Mons striker Jérémy Perbet to score the opening goal after just two minutes.

[51] With that, OHL moves into 8th place, seemingly headed for a safe mid-table position as the gap with the relegation zone has grown to 11 points.

Although Karel Geraerts manages to equalise after an early goal by Gent, OHL fails to win, as the home game ends in a 1–1 draw.

Ibou scored the goal for OHL after a fast counterattack and as OH Leuven had several opportunities, coach Van Geneugden states:"I have congratulated my players after the match because we should be proud of our achievement today".

[59] With the winter transfer window opening, several teams in the Belgian Pro League decide to make some changes in their personnel.

Due to several minor injuries, Boi had played only a few matches and had asked to be transferred and not to participate in the winter training camp with the rest of the team in Malta.

[64] Although Waasland-Beveren only played with 10 players for almost 35 minutes after a red card, the non-winning streak continues and grows to 11 matches as OH Leuven loses 2–0 in Beveren.

[69] OHL again fails to win one week later against bottom league team Beerschot, with a late equalizer by Benito Raman cancelling out the goal by Ibou.

[75] The month of April starts with the news that Icelandic midfielder Stefán Gíslason signs a new contract to keep him with Leuven for another season, until 2014.

After finishing 10th during the regular season, OHL was placed in Group B of the Europa League Playoff together with Mechelen, Charleroi and Waasland-Beveren.