The 2012 Dothan Pro Tennis Classic was a professional tennis tournament played on clay courts.

It was the twelfth edition of the tournament which was part of the 2012 ITF Women's Circuit, offering a total of $50,000 in prize money.

It took place in Dothan, Alabama, United States, on April 16–22, 2012.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following players received entry by a junior exempt: