The 2012 Open GDF Suez Nantes Atlantique was a professional tennis tournament played on indoor hard courts.

It was the tenth edition of the tournament which was part of the 2012 ITF Women's Circuit.

It took place in Nantes, France, on 29 October–4 November 2012.

The following players received wildcards into the singles main draw: The following players received entry from the qualifying draw: The following player received entry by a Protected Ranking: The following player received entry by a Junior Exempt: The following player received entry as a Lucky loser: