The 2012 Pan American Handball Championship, also called PanAmericano 2012, was the 15th official competition for senior men's national handball teams of North, Center, Caribbean and South America.

A decision was announced during the 2011 Pan American Games that the tournament will consist of 12 teams.

[1] As the winner of those Pan American Games, Argentina was selected as the host.

[2] Argentina Chile Greenland United States Venezuela Brazil Dominican Republic Mexico Paraguay Uruguay The Dominican Republic team withdrew after the draw, reportedly for financial reasons.

[3] All times are local (UTC−3) Points gained in the preliminary round against teams from the same group were carried over.