The 2016 Pan American Men's Handball Championship was the 17th official competition for senior men's national handball teams of North, Center, Caribbean and South America.

It was held from 11 to 19 June 2016 at the Tecnópolis in Buenos Aires, Argentina.

[1] Brazil won the tournament for the third time after defeating Chile 28–24 in the final.

[2] Venezuela was originally qualified but withdrew due to economic trouble.

The Pan-American Team Handball Federation chose Mexico to replace it.