The 2015–16 season was Bihor Oradea's 57th season in the Romanian football league system, and their 37th season in the Liga II.

On 12 January 2016, during the winter break, the club was declared bankrupt, after serious financial problems and several months in which the club lived from one day to the next.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.