The 2015–16 Youngstown State Penguins men's basketball team represented Youngstown State University during the 2015–16 NCAA Division I men's basketball season.

The Penguins, led by eleventh-year head coach Jerry Slocum, played their home games at the Beeghly Center in Youngstown, Ohio and were members of the Horizon League.

[1] They lost to Detroit in the first round of the Horizon League tournament.

[3] They lost to Detroit in the first round of the Horizon League tournament.

[4] After the 2014–15 season, guard Marcus Keene transferred to Central Michigan.