The tournament comprised a total of 36 teams, and the winner, Junior, who defeated Santa Fe 2–1 on aggregate score in the final, earned a berth to the 2016 Copa Sudamericana.
Unlike the previous seven Copa Colombia editions, the 2015 competition featured a change in its format.
The 8 group winners plus the best 4 second-placed teams joined the teams qualified for the 2015 Copa Libertadores (Atlético Nacional, Santa Fe, and Once Caldas) and the 2014 aggregate table best team not qualified for the Copa Libertadores (Águilas Doradas) in the round of 16, from where the cup continued on a home-and-away knockout basis.
Each tie in the knockout phase is played in home-and-away two-legged format.
Atlético Nacional, Santa Fe, Once Caldas, and Águilas Doradas entered the competition in the Round of 16, being joined there by the eight group winners and the four best second-placed teams.