The 2016–17 Greek A1 Ethniki was the 35th season of the A1 Ethniki, Greece's premier handball women's league.

A total of 10 teams participated in this year's edition of the Women's A1 Ethniki.

Of these, 6 sides qualified directly from the 2015–16 season, while 4 sides qualified from the A2 Ethniki play-offs: Panetolikos, Arion Ptolemaida, Honda Panorama and Filippos Veria.

The team that finished in the higher championship play-off place, is going to play the first, second and fifth (if necessary) game of the series at home.

[2] Source: Hellenic Handball Federation