The 2015 Charleston Southern Buccaneers football team represented Charleston Southern University as a member of the Big South Conference during the 2015 NCAA Division I FCS football season.

Led by Jamey Chadwell in his fourth and final season as head coach, the Buccaneers compiled an overall record of 7–4 with a mark of 4–1 in conference play, sharing the Big South title with Liberty.

Charleston Southern earned the conference's automatic bid to the NCAA Division I Football Championship playoffs, where the Buccaneers lost in the first round to Wofford.

Charleston Southern played home games at Buccaneer Field in Charleston, South Carolina.

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