The final would be played on a home-and-away two-legged basis, with the higher-seeded team hosting the second leg.

[1] On 28 November 2016, LaMia Flight 2933, carrying the Chapecoense squad to the first leg, crashed on the way to the José María Córdova International Airport.

[9] CONMEBOL immediately suspended all activities, including the scheduled final matches, in the early morning of 29 November.

[4][12] Atlético Nacional invited fans to the Estadio Atanasio Girardot dressed in white with candles at the scheduled time of the first leg, to pay tribute in memory to the victims of the crash.

[15][16] Services were held in both the Estádio Couto Pereira, and Chapecoense's stadium, the Arena Condá, on the night that the second leg was scheduled.