The Cleveland Cavaliers had the best record in the Eastern Conference, but on January 22, the team fired head coach David Blatt and replaced him with Tyronn Lue.

Dwyane Wade of the Miami Heat was also named a starter to his 12th career All-Star Game, with a total of 941,466 votes.

[4] The West Reserves included Klay Thompson and Draymond Green of the Golden State Warriors, Chris Paul of the Los Angeles Clippers, James Harden of the Houston Rockets, Anthony Davis of the New Orleans Pelicans, DeMarcus Cousins of the Sacramento Kings, and LaMarcus Aldridge, who made the All-Star Game as a member of the San Antonio Spurs for the first time.

The East Reserves included John Wall of the Washington Wizards, DeMar DeRozan of the Toronto Raptors, Jimmy Butler of the Chicago Bulls, Isaiah Thomas of the Boston Celtics, Chris Bosh of the Miami Heat, Paul Millsap of the Atlanta Hawks, and Andre Drummond of the Detroit Pistons.

Jimmy Butler and Chris Bosh ultimately had to sit out the All-Star Game due to a knee and calf injury, respectively.

Pau Gasol of the Chicago Bulls and Al Horford of the Atlanta Hawks were named as Butler and Bosh's replacements.

[9] Russell Westbrook earned his second-straight MVP award in his first All-Star start as the West won 196–173 over the East.

Kobe Bryant, who planned to retire after the season, had 10 points, six rebounds, and seven assists in his final All-Star Game.

[11] Stephen Curry added 26 points for the West, and teammates Anthony Davis scored 24 on 12-of-13 shooting and Kevin Durant tallied 23.

Team USA, coached by Canadian rapper Drake, and 4-time Celebrity Game MVP Kevin Hart, respectively.

It featured 21 players, including actors Stephan James, Jason Sudeikis, Anthony Anderson, O'Shea Jackson, Jr., Joel David Moore, and Tom Cavanagh, and TV hosts Nick Cannon, Terrence Jenkins, and the Property Brothers.

The game also included four NBA legends in Chauncey Billups, Muggsy Bogues, Tracy McGrady, and Rick Fox, as well as Elena Delle Donne and Tammy Sutton-Brown of the WNBA.

[24] Teammates Stephen Curry and Klay Thompson of the Golden State Warriors, known as the Splash Brothers, were the favorites to win the contest.